University of Khartoum

Comparative Efficacy of Mebendazole, Cucubita maxima and Tapinex against Raillietina tetragona Infection in Chickens

Comparative Efficacy of Mebendazole, Cucubita maxima and Tapinex against Raillietina tetragona Infection in Chickens

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Title: Comparative Efficacy of Mebendazole, Cucubita maxima and Tapinex against Raillietina tetragona Infection in Chickens
Author: Sanaa Mohamed El Tayeb Ali., Ali
Abstract: Comparative efficacies of mebendazole (Erizole), tapinex (niclosamide) and seeds of the medicinal plant Cucurbita maxima were evaluated in Bovans type chicks experimentally infected with the tapeworm Raillietina tetragona. Treatment started 21 days post infection and levels of effectiveness of tapinex in oral doses of (200- 2000 mg/kg/day), mebendazole (100-300 mg/kg/day) and seeds of C. maxima at (25-75%) of the basal diet for 3 or 7 consecutive days against the tapeworm were estimated. Efficacies against tapeworm were for mebendazole 100%, tapinex 81.8-100% and C. maxima seeds 8.18-19.09%. R. tetragona infection in chicks caused mild enteritis, congestion of the mesenteric blood vessels, and erosions on the intestinal epithelium. In chicks treated with tapinex, mebendazole and C. maxima, lesions were less marked, and correlated with changes in haematology (RBC, PCV, Hb, MCV and MCHC), serobiochemistry (AST, ALP, triglyceride, creatinine, bilirubin and total protein), carcass characteristics and meat quality attributes (cooking loss, water-holding capacity, colour, shearforce and pH).
URI: http://khartoumspace.uofk.edu/handle/123456789/15445
Date: 2015-06-28


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