University of Khartoum

Occupational Hazards and HBV infection among health care workers in Public Teaching Hospitals in Khartoum State, Sudan: A multiple Discriminant Analysis

Occupational Hazards and HBV infection among health care workers in Public Teaching Hospitals in Khartoum State, Sudan: A multiple Discriminant Analysis

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Title: Occupational Hazards and HBV infection among health care workers in Public Teaching Hospitals in Khartoum State, Sudan: A multiple Discriminant Analysis
Author: Elmukashfi,Taha Ahmed; Isam Mohamed Elkhidir; Omer Ali Ibrahim; Abdelgadir Ali Bashir; Mohammed Ali Awad Elkarim
Abstract: Background: Infection with HBV leads to a wide spectrum of liver injury. It ranges from acute self-limited infection and fulminant hepatitis to chronic hepatitis. Objectives: To examine the prevalence of sero-epidemiologic markers of hepatitis B virus and to identify the risk factors of exposure to HBV among health care workers in Public Teaching Hospitals in Khartoum State, Sudan; in 2004. Methods: The study was a cross sectional, facility-based study. It was conducted on stratified twostage cluster sampling of 843 subjects. The study adopted multivariate statistical approach, using Multiple Discriminant Analysis (MDA) and some non-parametric tests. Results: Infection rate measured by Anti-HB core, carrier rate measured by HBs Ag, and a profile of high infectivity rate measured by HBe Ag was found to be high; while immunity rate measured by Anti-HBs was found to be low. Needle stick injury, contaminated sharp instruments injury and exposure to blood are the most significant occupational variables related to infection rate of HBV. Contaminated sharp instruments injury and exposure to blood, are the most significant occupational variables related to carrier rate. Date of needle stick injury, incidence and date of contaminated sharp instruments injury, incidence and date of exposure to blood have significant relation to immunity rate against HBV infection. Conclusion: The prevalence rate of HBV markers among HCWs in Public Teaching Hospitals in Khartoum State, Sudan, differs according to occupational hazard factors. With the exception of the HBeAg, seroprevalence of all HBV markers was found to be significantly correlated with occupational hazards (P<0.05).
URI: http://khartoumspace.uofk.edu/123456789/16295
Date: 2012-03


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