University of Khartoum

Misdiagnosis and Mistreatment of Post-Kala- Azar Dermal Leishmaniasis

Misdiagnosis and Mistreatment of Post-Kala- Azar Dermal Leishmaniasis

Show simple item record El Hassan, Ahmed M. Khalil, Eltahir Awad G. El Hassan,Lamyaa
dc.contributor.editor A. Chow en_US 2013 2015-11-12T10:00:01Z 2015-11-12T10:00:01Z 2015-11-12 2015
dc.description.abstract This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Post-kala-azar dermal leishmaniasis (PKDL) is a known complication of visceral leishmaniasis (VL) caused by L. donovani. It is rare in VL caused by L. infantumand L. chagasi. In Sudan, it occurs with a frequency of 58% among successfully treated VL patients. In the majority of cases, PKDL can be diagnosed on the basis of clinical appearance, distribution of the lesions, and past history of treated VL. The ideal diagnostic method is to demonstrate the parasite in smears, by culture or PCR. Diagnosis is particularly difficult in patients who develop PKDL in the absence of previous history of visceral leishmaniasis.We describe a case of cutaneous leishmaniasis misdiagnosed as PKDL and 3 cases of PKDL who were either misdiagnosed or mistreated as other dermatoses.This caused exacerbation of their disease leading to high parasite loads in the lesions and dissemination to internal organs in one of the patients, who was also diabetic.The latter patient had L. major infection. A fourth patient with papulonodular lesions on the face and arms of 17-year duration and who was misdiagnosed as having PKDL is also described. He turned out to have cutaneous leishmaniasis due to L. major. Fortunately, he was not treated with steroids. He was cured with intravenous sodium stibogluconate. en_US
dc.publisher university of khartoum en_US
dc.subject Misdiagnosis and Mistreatment of Post-Kala-Azar Dermal Leishmaniasis en_US
dc.title Misdiagnosis and Mistreatment of Post-Kala- Azar Dermal Leishmaniasis en_US
dc.type Publication en_US
dc.Faculty Endemic Diseases en_US

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