Title:
|
Primary Cutaneous Follicular Lymphoma Associated with Helicobacter pylori Infection |
Author:
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Ibrahim, Muntaser E.; Alfarouk, Khalid Omer; Yousif, Sabah; etal.
|
Abstract:
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A 66 year o ld male with a long standing uncontrolled gastric H pylori infection and Crohn’s disease presented
with nodular lesions in the back. These were removed surgically. Pathologically the lesion consisted of lymphocytes, giant
cells with vacuolated cytoplasm and histiocytes. By immunohistochemistry there were stem cells, B cells and CD1a
Langerhans cells. The diagnosis of Langerhans histiocytosis was made. The giant cells were positive for both CD 20 B cell
marker and the macrophage marker CD 68 indicating that they were derived from B cells. They were strongly positive for H
pylori antigen. A year later the patient reported with non-itching nodular lesions in the right flank. There was no
lymphadenopathy or Splenomegaly. A biopsy of the lesion showed a follicular center B cell lymphoma. The tumor cells were
positive for H pylori antigen. He was treated for H pylori infection. He completely recovered and was in good health a year
later. |
URI:
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http://khartoumspace.uofk.edu/123456789/17226
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Date:
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2015-11-18 |