University of Khartoum

Granulomatous Mammary Disease: ten years’ Experience with Fine Needle Aspiration Cytology

Granulomatous Mammary Disease: ten years’ Experience with Fine Needle Aspiration Cytology

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Title: Granulomatous Mammary Disease: ten years’ Experience with Fine Needle Aspiration Cytology
Author: Elsiddig, K. E.; Khalil, Eltahir Awad G.; Elhag, I. A.; etal.
Abstract: To determine the aetiological types of granulomatous disease of the breast in women presenting with mammary complaints in the Sudan. METHODS: Clinical history and physical examination, complete blood counts, Mantoux test, histopathology and fine needle aspiration cytology (FNAC). RESULTS: Granulomatous mastitis was seen in 11/2500 (0.44%) patients with mammary disease over a 10-year period. All were of childbearing age (mean 26.0 5.9 years). Common presentations were diffuse swelling, well-circumscribed masses, nipple retraction, multiple sinuses and superficial skin ulcers. Lymphadenopathy was seen in more than 60% of the patients. Diagnosis was based on cytomorphological features in 10/11 cases and histopathology in one. Nine were diagnosed with tuberculous mastitis and two with idiopathic granulomatous mastitis. Acid-fast bacilli (AFB) could not be demonstrated in any of the cytology smears. Tuberculous mastitis responded to empirical anti-tuberculosis treatment, with a minimum follow-up of 2 years in seven women. CONCLUSION: Tuberculous mastitis is a rare entity in women with mammary disease in the Sudan. Alternative diagnoses such as idiopathic granulomatous mastitis should be made only after failure of an adequate trial of anti-tuberculosis treatment. FNAC is a useful diagnostic tool even if AFB cannot be demonstrated.
URI: http://khartoumspace.uofk.edu/123456789/17247
Date: 2015-11-19


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