University of Khartoum

A preliminary Study on the Ultrastructure of Actinomadura Pelletieri and its Host Tissue Reaction

A preliminary Study on the Ultrastructure of Actinomadura Pelletieri and its Host Tissue Reaction

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dc.contributor.author Elhassan, Ahmed M
dc.contributor.author Fahal, Ahmed H
dc.contributor.author El Toum, E. A
dc.date 1994
dc.date.accessioned 2015-11-29T07:59:28Z
dc.date.available 2015-11-29T07:59:28Z
dc.date.issued 2015-11-29
dc.date.submitted 2015-11-29
dc.identifier.uri http://khartoumspace.uofk.edu/123456789/17328
dc.description.abstract This is the first report on the fine structure of Actinomadura pelletieri. The in vitro ultrastructure of the organism and that of the grain in vivo were similar. The grain consisted of packed filaments with a faintly electron-dense matrix in between. The individual filament was septate, the cytoplasm was either vacuolated or contained intracellular organelles and the cytoplasmic membrane was adherent to the filamentous wall, which has three electron-dense and two electron-lucent layers. The absence of cement substance around the grain may partially explain the aggressive and destructive behaviour of this organism and may probably also explain its good response to medical treatment. The inflammatory host reaction was similar to that seen with all mycetoma organisms except that there was a massive neutrophil reaction. This was confirmed by electron microscopy. en_US
dc.language.iso en en_US
dc.publisher Oxford Journals en_US
dc.subject Actinomadura en_US
dc.subject Host en_US
dc.subject ultrastructure en_US
dc.title A preliminary Study on the Ultrastructure of Actinomadura Pelletieri and its Host Tissue Reaction en_US
dc.type Publication en_US
dc.Faculty Endemic Diseases en_US

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