University of Khartoum

Diversity among Leishmania Isolates from the Sudan: Isoenzyme Homogeneity of L. donovani Versus Heterogeneity of L. major

Diversity among Leishmania Isolates from the Sudan: Isoenzyme Homogeneity of L. donovani Versus Heterogeneity of L. major

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Title: Diversity among Leishmania Isolates from the Sudan: Isoenzyme Homogeneity of L. donovani Versus Heterogeneity of L. major
Author: Elhassan, Ahmed M
Abstract: Leishmania isolates from patients in the Sudan suffering from either visceral or cutaneous leishmaniasis were characterized using a battery of 12 enzymes. Aspartate aminotransferase separated the L. donovani isolates into 2 distinct zymodemes, but the overall results showed no significant geographical variation among L. donovani isolates. In contrast, the isolates of L. major were polymorphic, exhibiting differences in nucleoside hydrolase, 6-phosphogluconate dehydrogenase, superoxide dismutase, esterase, mannose phosphate isomerase, and aspartate aminotransferase, resulting in the description of 4 new enzymatic variants
URI: http://khartoumspace.uofk.edu/123456789/17350
Date: 2015-11-29


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