University of Khartoum

Toxicity of Calotropis procera latex in pregnant and non-pregnant goats

Toxicity of Calotropis procera latex in pregnant and non-pregnant goats

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Title: Toxicity of Calotropis procera latex in pregnant and non-pregnant goats
Author: ElBadwi, S.M.A.; Bakhiet, A. O.
Abstract: Experiments were carried out to examine the effect of Calotropis procera latex on pregnant and nonpregnant Nubian goats. In pregnant goats during 2 - 3 months of pregnancy, the latex was given at 0.3 ml/kg/day intra vaginally, the animals showed small amounts of mucus at the vulva and plugs, cried in pain and there was maternal and fetotoxicity on day 3 of the experiment. The toxicity was correlated with pathological changes which include higher activities of aspartate aminotransferase (AST), alkaline phosphatase (ALP) and higher concentrations of creatinine, globulin, urea and progesterone while in non-pregnant goats given C. procera latex at 0.3 ml/kg/day or at 0.005 ml/kg/day intravaginally, showed vaginitis, anorexia and loss of condition..
URI: http://khartoumspace.uofk.edu/handle/123456789/17774
Date: 2015-12-17


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