University of Khartoum

Hepatitis B Virus, Hepatitis C Virus and Human Immunodeficiency Virus Infections among Pregnant Women in Central Sudan

Hepatitis B Virus, Hepatitis C Virus and Human Immunodeficiency Virus Infections among Pregnant Women in Central Sudan

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dc.contributor.author Mirghani, O.A.
dc.contributor.author Adam, I.
dc.contributor.author Gasim, G.I.
dc.contributor.author Osman, A.M.M
dc.contributor.other Department of Obstetrics and Gynecology en_US
dc.date 2014
dc.date.accessioned 2016-01-13T07:56:30Z
dc.date.available 2016-01-13T07:56:30Z
dc.date.issued 2016-01-13
dc.date.submitted 2016
dc.identifier.uri http://khartoumspace.uofk.edu/handle/123456789/18449
dc.description.abstract Background: The epidemiology of viral hepatitis and Human immunodeficiency virus (HIV) during pregnancy is of great importance for health planners and program managers. However, few published data on viral hepatitis and HIV are available in Sudan especially during pregnancy. Objectives: The current study was conducted to investigate seropositivity of hepatitis B, hepatitis C, and HIV among pregnant women in central Sudan. Materials and methods: A cross sectional study was conducted where 396 pregnant women were investigated for the presence of hepatitis B, C and HIV. Enzyme linked immunosorbent assay (ELISA) was used to detect HBsAg and anti-HCV. Antibodies to HIV were detected by three different methods as per Strategy III of the National AIDS Control Organization by utilizing different systems of testing to make a diagnosis of HIV. Results: Twenty (5.1%), five (1.3%), and six (1.5%) women were seropositive for HBsAg anti- HCV antibodies and HIV, respectively. One (0.003 %) woman was seropositive for both HBsAg and anti-HCV antibodies. While age, parity, were not associated with seropostivtiy of HBsAg, home delivery was the only significant risk factor for seropostivtiy of HBsAg (OR=4.5 (95% CI=1.2-16.7) Conclusion: Prevalence of HBV and HCV among pregnant women in this setting is in the intermediate zone of endemicity. This is alarming and should draw medical authorities’ attention if vertical transmission is to be reduced. en_US
dc.language.iso en en_US
dc.publisher University of Khartoum en_US
dc.subject Sudan en_US
dc.subject hepatitis B en_US
dc.subject hepatitis C en_US
dc.subject HIV en_US
dc.subject seropositivity en_US
dc.subject Pregnancy en_US
dc.title Hepatitis B Virus, Hepatitis C Virus and Human Immunodeficiency Virus Infections among Pregnant Women in Central Sudan en_US
dc.type Publication en_US
dc.Faculty Medicine en_US

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