University of Khartoum

A pilot study of antioxidant potential of endophytic fungi from some Sudanese medicinal plants

A pilot study of antioxidant potential of endophytic fungi from some Sudanese medicinal plants

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dc.contributor.author Yagi, Sakina
dc.contributor.author Khiralla, Afra
dc.date 2015
dc.date.accessioned 2016-02-25T10:28:41Z
dc.date.available 2016-02-25T10:28:41Z
dc.date.issued 2016-02-25
dc.date.submitted 2016
dc.identifier.uri http://khartoumspace.uofk.edu/handle/123456789/19433
dc.description.abstract To evaluate the total phenolic content (TPC) and total antioxidant capacity (TAC) of ethyl acetate extracts of 21 endophytic fungi isolated from five Sudanese medicinal plants: Calotropis procera (C. procera), Catharanthus roseus (C. roseus), Euphorbia prostrate (E. prostrata), Vernonia amygdalina (V. amygdalina) and Trigonella foenum-graecum (T. foenum-graecum). Methods: Crude extracts of endophytic fungi and their host plants were tested by classical Folin-Ciocalteu colorimetric method to determine the TPC, also TAC was estimated using DPPH (1,1-diphenyl-2-picrylhydrazyl) free radical scavenging in vitro method. Results: Among the endophytes, endophytic fungus Aspergillus sp. from T. foenum-graecum seeds demonstrated the highest both total phenolic content in term of Gallic Acid Equivalent (89.9±7.1 mg GAE/g) and antioxidant activity for DPPH radical scavenging assay (IC50:18.0±0.1 μg/mL). A high positive linear correlation (R2=0.999 1) was found between TAC and TPC of endophytic fungi isolated from V. amygdalina. Conclusion: The present study revealed that some endophytic fungi from the five Sudanese medicinal plants could be a potential source of novel natural antioxidant compounds en_US
dc.publisher uofk en_US
dc.subject Sudanese medicinal plants Endophytic fungi Antioxidant activity Total phenolic content en_US
dc.title A pilot study of antioxidant potential of endophytic fungi from some Sudanese medicinal plants en_US
dc.type Publication en_US
dc.Faculty Science en_US

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