University of Khartoum

Identification and In vitro Evaluation of New Antileishmanial Drugs using Bioinformatics

Identification and In vitro Evaluation of New Antileishmanial Drugs using Bioinformatics

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Title: Identification and In vitro Evaluation of New Antileishmanial Drugs using Bioinformatics
Author: Gindeel, HAMA; Mukhtar, MM; Shaddad, SA
Abstract: Leishmaniasis is a major public health problem in several parts of the world. It is caused by the obligate intracellular protozoan parasite of the genus leishmania and is transmitted by the female sand fly of the genera phlebotomus and lutzomyia. It presents in different clinical forms: cutaneous (CL) diffuse cutaneous (DCL), visceral (VL), mucocutaneous (MCL), mucosal (ML) or post kalazar dermal leishmaniasis (PKDL). Leishmaniasis is difficult to treat and there is increasing resistance developing against the currently available drugs which are toxic, expensive, given by injection and require hospitalization for long durations.
URI: http://khartoumspace.uofk.edu/handle/123456789/19585
Date: 2015


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