University of Khartoum

Epidemiology Of Hepatitis B And Hepatitis C Virus Infections In Pregnant Women In Sana’a, Yemen

Epidemiology Of Hepatitis B And Hepatitis C Virus Infections In Pregnant Women In Sana’a, Yemen

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Title: Epidemiology Of Hepatitis B And Hepatitis C Virus Infections In Pregnant Women In Sana’a, Yemen
Author: Murad, Entisar A.; Babiker, Suad M.; Gasim, Gasim I.; Rayis, Duria A.; Adam, Ishag
Abstract: Background: Screening for Hepatitis B and C during pregnancy may help to decide on appropriate antiviral therapy and the institution of steps to minimize vertical transmission to the newborn infants. Methods: A cross-sectional study was conducted during November–December 2011 to investigate the seroprevalence and associated risk factors for markers of HBV (hepatitis B surface antigen; HBsAg) and anti-HCV antibody among pregnant women at the Al-Thawra hospital in Sana’a, Yemen. Structured questionnaires were used to obtain sociodemographic obstetrics and medical data and sera were tested for HBsAg and anti-HCV. Results: Of the 400 pregnant women enrolled in the study, HBsAg and anti-HCV were detected in 43 (10.8%; 95% CI: 8.0–14.0%) and 34 (8.5%, 95% CI: 6.0–11.5%) women, respectively. None of the women were co-infected with HBV and HCV. Multivariate analysis showed that circumcision was significantly associated with HBsAg seropositivity (OR = 3.3, 95% CI: 1.1–10.2; p = 0.03), low parity (primigravidae and secundigravidae) and education below secondary level were significantly associated with anti- HCV seropositivity (OR = 3.3, 95% CI: 1.1–10.2; p = 0.03). No other sociodemographic or clinical characteristics (age, residence, history of home delivery, miscarriage, dental manipulation, surgery, and blood transfusion) were significantly associated with HBsAg or anti-HCV seropositivity. Conclusion: The results of this study suggest that HBsAg and anti-HCV have high prevalence among pregnant women.
URI: http://khartoumspace.uofk.edu/handle/123456789/20838
Date: 2016-04-26


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