University of Khartoum

Papillon-Lefèvre Syndrome: A Report of Three Siblings

Papillon-Lefèvre Syndrome: A Report of Three Siblings

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Title: Papillon-Lefèvre Syndrome: A Report of Three Siblings
Author: Muddathir, Abdelkhalig
Abstract: We reported an 18 year old Sudanese female patient, Gaali tribe, and another 2 males, brothers ages 10 and 8 years old, presented with diffuse trangrediens palmoplantar keratosis with scaly, non-erythematous, psoriasiform-like transgradient plaque in elbows and knees, and periodontosis, the female patient has been misdiagnosed before as a case of Psoriasis and given phototherapy in the form of PUVA with satisfactory results and the 2 brothers has been also missed as a cases of eczemas with poor response to treatment and frequent relapses. The female case is associated with thyroid swelling and increased Thyroid Stimulating Hormone TSH, and considered as a first cases record at Sudan, as Papillon-Lefèvre syndrome is known as a rare presentation globally and in Sudan specifically
URI: http://khartoumspace.uofk.edu/123456789/21757


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