University of Khartoum

Antidiarrhoeal Activity Of Ethanolic Extract Of Adansonia Digitata Fruit Pulp In Rats.

Antidiarrhoeal Activity Of Ethanolic Extract Of Adansonia Digitata Fruit Pulp In Rats.

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Title: Antidiarrhoeal Activity Of Ethanolic Extract Of Adansonia Digitata Fruit Pulp In Rats.
Author: Abdelrahim, Maha Y.; Elamin, Babiker M. A.; Khalil, Dalia J.; El Badwi., Samia M. A.
Abstract: The antidiarrhoeal activity of ethanolic extract of Adansonia digitata fruit pulp was evaluated in rats. Studies were investigated on castor oil - induced diarrhoea , castor oil induced fluid accumulation and electrolyte secretion. Adansonia digitata was orally administered to rats at dose rate of 250 and 500mg/kg and Loperamide was us ed at 3mg/kg as reference antidiarrhoeal drug.The extract produced a dose dependant and significantly protected rats against castor oil induced diarrhoea . The frequency of defecation as well as weight of the feces was significantly (p>0.05) reduced.A prel iminary phytochemical screening of the ethanolic extract of A. digitata revealed the presence of, flavonoids, saponins, tannins triter penes, alkaloids and glycosides .
URI: http://khartoumspace.uofk.edu/123456789/21780


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