Title:
|
DGAT1 Gene in Dairy Cattle |
Author:
|
Mohammed, Safa A.; Rahamtalla, Siham A.; Ahmed, Salah S.; Elhafiz, A.; Dousa, Bakhiet M.; Elamin, Khalid M.; Ahmed, M.K.A.
|
Abstract:
|
The interest in the bovine DGAT1 gene has increased during the last few
years. DGAT1 gene, encodes a microsomal enzyme that by using
diacylglycerol and fatty acyl CoA as substrates catalyzes the terminal and
committed step of triacylglycerol biosynthesis. This step is the most important
storage form of energy for eukaryotic cells. DGAT1 is also important for the
physiological processes involving triacylglycerol metabolism such as
intestinal fat absorption, lipoprotein assembly, adipose tissue formation and
lactation. Lactation was impaired in female mice lacking both copies of
DGAT. This observation leads to a suggestion that DGAT1 gene was the
functional candidate gene for milk production traits. The frequency of
polymorphism in DGAT1 gene has been found to be very high in dairy cattle.
Some associated studies such as, milk yield, fat content, protein yield and
content have been carried out in dairy cattle. These associations will provide
insight in to the underlying mechanism of DGAT1 gene and polymorphisms
that can be used for selection purposes in dairy cows. |
Description:
|
8 Pages |
URI:
|
http://khartoumspace.uofk.edu/123456789/21785
|