University of Khartoum

Effects of Camel Urine on Serum Testosterone Level in Male Rats of Different Testosterone Levels

Effects of Camel Urine on Serum Testosterone Level in Male Rats of Different Testosterone Levels

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Title: Effects of Camel Urine on Serum Testosterone Level in Male Rats of Different Testosterone Levels
Author: Mohamed, Dalia A.; El Bagir, Nabiela M.; Khougali, Salawa M.E.
Abstract: Twenty four adult Wistar albino male rats, weighing 140-200 g were used to evaluate the effect of oral administration of she-camel urine in rats of different testosterone levels. The rats were divided into four groups; high serum testosterone group (HT) and low serum testosterone group (LT), prepared by subcutaneously injection of testosterone enanthate and intraperitoneally injection of lead acetate respectively for 21 days and other two groups (Normal Testosterone (NT) and Control (C)) were used without pre treatments. Then, all groups except the control group were treated daily by an oral dose of 2 mL/100 g body weight of she-camel urine for another 21 days. Rat's body weight was measured and blood samples were taken, before camel urine treatment and weekly after camel urine to determine the serum levels of testosterone. The results revealed that, camel urine regulated the high and low serum testosterone levels as they returned to their normal values. At the same time, no change on testosterone level was seen in the group of NT. After the 1st 2 weeks of the treatment HT group showed significant decrease in the serum testosterone level from 21.60-14.5 ng mL-1 while LT group appeared significant increase from 2.55-7.28 ng mL-1. In the 3rd week, all treated groups showed significant (p<0.01) increase in testosterone level compared to the previous week. Camel urine treatment also improved the rate of weight growth in rats compared to the pretreated period in HT and LT groups. The study concluded that camel urine can regulate serum testosterone levels and rectify the resulted changes accompanied abnormal hormone levels.
URI: http://khartoumspace.uofk.edu/123456789/21848


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