University of Khartoum

Alterations in Thermoregulation and Haematological Indices in Alloxan -Diabetic Rabbits (Lepus Cuniculus) in Relation to Dietary Starch and Season

Alterations in Thermoregulation and Haematological Indices in Alloxan -Diabetic Rabbits (Lepus Cuniculus) in Relation to Dietary Starch and Season

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Title: Alterations in Thermoregulation and Haematological Indices in Alloxan -Diabetic Rabbits (Lepus Cuniculus) in Relation to Dietary Starch and Season
Author: Ibrahim, Mariam Y; Abdelatif, Abdalla Mohamed
Abstract: The aim of this study was to evaluate the effects of starch supplementation and season (summer vs winter) on thermoregulation, body weight (BW), water consumption and haematological parameters in alloxan-inuced diabetic and non-diabetic rabbits. Starch supplementation increased rectal temperature (Tr) of diabetic groups significantly during summer; in winter, (Tr) in non-diabetic rabbits fed Lucerne was significantly lower than other groups. During summer, non-diabetic starch-supplemented rabbits had significantly higher respiratory rate (RR) than other groups. RR values of experimental groups were significantly higher in summer compared with the respective winter values. In both seasons, diabetic starch-supplemented rabbits had lower body weight (BW) compared to the other groups. During summer, diabetic starch-supplemented rabbits had the lowest (BW). The diabetic group of rabbits fed Lucerne and starch had significantly higher (BW) during winter compared to the respective summer value. In both seasons, diabetic groups of rabbits had significantly higher water consumption compared to the non-diabetic groups. Starch supplementation increased water consumption significantly in diabetic rabbits. Water consumption of non-diabetic group of rabbits fed Lucerne and diabetic groups was significantly higher during summer compared with respective winter values. In both seasons, diabetic groups of rabbits had lower packed cell volume (PCV) and haemoglobin concentration (Hb)compared to the respective values of non-diabetic rabbits. Non-diabetic rabbits fed Lucerne had significantly higher Hb value during winter compared to summer value. During winter, non-diabetic rabbits fed Lucerne had significantly lower total leukocyte count (TLC) compared to values of other groups. Non-diabetic groups had significantly higher (TLC) values during summer compared to winter values. In diabetic groups, winter values of (TLC) were higher compared to summer value. The findings are relevant to the pathophysiological changes in human diabetes.
URI: http://khartoumspace.uofk.edu/123456789/21854


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