University of Khartoum

Antidiabetic Effects of Fenugreek (Trigonella foenum-graecum) Seeds in the Domestic Rabbit (Oryctolagus cuniculus)

Antidiabetic Effects of Fenugreek (Trigonella foenum-graecum) Seeds in the Domestic Rabbit (Oryctolagus cuniculus)

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Title: Antidiabetic Effects of Fenugreek (Trigonella foenum-graecum) Seeds in the Domestic Rabbit (Oryctolagus cuniculus)
Author: Abdelatif, Abdalla Mohamed; Ibrahim, Mariam Y; Mahmoud, Amal S.
Abstract: Adult male rabbits were used to evaluate the effects of supplementation with fenugreek seeds on Body Weight (BW), plasma glucose and serum levels of cholesterol and insulin in alloxan-induced diabetic and in non-diabetic rabbits. Diabetic and non-diabetic groups of rabbits supplemented with fenugreek showed a slight increase in BW. Supplementation with fenugreek resulted in a significant decrease in glucose level of diabetic group of rabbits and a slight effect in non-diabetic rabbits. Diabetic groups of rabbits had significantly higher serum cholesterol levels compared to non-diabetic groups. Supplementation with fenugreek lowered the cholesterol level slightly in diabetic groups. The alloxan-treated groups of rabbits maintained significantly lower serum insulin level compared to the respective values obtained for the non-diabetic groups. Supplementation with fenugreek slightly increased serum insulin level in diabetic rabbits. The findings demonstrate the antidiabetic and insulin mimetic effects of fenugreek seeds in rabbits.
URI: http://khartoumspace.uofk.edu/123456789/21857


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