University of Khartoum

Thermoregulation, Heart Rate and Body Weight as Influenced by Thyroid Status and Season in the Domestic Rabbit (Lepus cuniculus)

Thermoregulation, Heart Rate and Body Weight as Influenced by Thyroid Status and Season in the Domestic Rabbit (Lepus cuniculus)

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Title: Thermoregulation, Heart Rate and Body Weight as Influenced by Thyroid Status and Season in the Domestic Rabbit (Lepus cuniculus)
Author: Abdelatif, Abdalla Mohamed; Saeed, Intisar H.
Abstract: The aim of this study was to investigate the effects of thyroid status and seasonal change in thermal environment on rectal temperature (Tr), respiratory rate (RR), heart rate (HR) and body weight (BW) in male rabbits. Thyroxine, T4 (30 μg/ kg BW /day) injected subcutaneously was used to induce hyperthyroidism and carbimazole, (CBZ) (30 mg / animal /day) administered orally, was used to induce hypothyroidism. During summer, (T4) treatment increased significantly (Tr), (RR), (HR) and decreased significantly (BW) compared with (CBZ). In all groups, (Tr) and (RR) values were higher and (BW) values were lower in summer compared to respective winter values. The group receiving (T4) had higher (Tr) in summer compared to winter. The control and (CBZ) treated group had higher and (T4) treated group had lower (HR) during winter compared to respective summer values. (T4) treatment significantly increased (HR) compared with control and (CBZ) values in summer. (T4) treated group had lower mean (BW) and (CBZ) treated group had higher mean (BW) compared to the respective control values; the mean (BW) was significantly lower with (T4) compared to the control. For all groups, the mean (BW) values were higher during winter. The findings have implications in therapy of thyroid disorders in mammals.
URI: http://khartoumspace.uofk.edu/123456789/22188


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