University of Khartoum

Association between Sickle Cell Disease and Malocclusion and Dental Caries among Sudanese Children

Association between Sickle Cell Disease and Malocclusion and Dental Caries among Sudanese Children

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Title: Association between Sickle Cell Disease and Malocclusion and Dental Caries among Sudanese Children
Author: Hussein, Maha Osman
Abstract: Background: Sickle cell disease is an autosomal recessive haemoglobinopathy predominant among Afro-descendants, and has been categorized as a public health issue as it affects a significant percentage of the world’s population. The aim of this study was to assess malocclusion and dental caries among a sample of Sudanese sickle cell disease children in relation to healthy control children. Methods: Malocclusion traits and caries index (dmft and DMFT) were recorded for 212 children with confirmed diagnosis of sickle cell disease (HbSS genotype). The children aged 4-14 years were selected trough simple randomization, matched to randomly selected healthy kindergarten and primary school children selected through multi-stage sampling, applied on the basis of birth date and gender. Age stratification was done according to the WHO into three age groups; children aged 4-6 years, 7-11 years and 2-14 years. Statistical analysis was done using statistical software SPSS 18 version. Chi square test & T test was used for the comparison of study and control groups, the level of significance was set at p<0.05. Results: The malocclusion traits were significantly higher in sickle cell disease children than healthy control children. The common malocclusion traits were Angle’s Class II and increased over jet children followed by anterior open bite. The malocclusion traits and relative risk were significantly more among sickle cell disease individuals of 12-14 years compared to the control group. The sickle cell disease group had significantly higher DMT and dmft than the control group (2.3 vs 0.7 for DMFT, 3.3 vs 1.8 for dmft). The dmft was significant among the age group 4-6 and 7-11 years while DMFT was significant among 12-14 years. Conclusion: Sudanese sickle cell disease children had increased susceptibility to dental caries and a higher prevalence of malocclusion. Recognition of their situation may contribute to the planning of dental service that decreases the incidence of dental caries and malocclusion.
Description: 68 Pages
URI: http://khartoumspace.uofk.edu/123456789/22935


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