University of Khartoum

Anti-Malarial Activity Of Khaya Senegalensis

Anti-Malarial Activity Of Khaya Senegalensis

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Title: Anti-Malarial Activity Of Khaya Senegalensis
Author: Shayoub, M. El. A; Kabbashi, Ahmed S.; Osman, Hisham Mohamed; Mahmoud, Asma Noureldaim; Elhassan5, Ali M.; A, Ahmed. M. El.; Dawoud, Azza Dawoud H.; Jawad, Alobosi Sabah Aziz; A, Sara, M. el., A.
Abstract: Malaria is one of the most common major health problems all over the world. Pharmacotherapy is the most common treatment strategy for the disease. Khaya senegalensis (Mahogany) belongs to the (family: Meliaceae). K. senegalensis was used in ethnomedicine for the treatment of various disease conditions such as rheumatoid arthritis, diarrhea cough, emetic, emmenagogue and in jaundice. This study was carried out to evaluate anti-malarial activity (Plasmodium falciparum) of K. senegalensis extract of methanol. The extracts of K. senegalensis were screened for its anti-malarial activites (Plasmodium falciparum) with different concentrations (500, 250 and 125 ppm) and Artemether (the reference control) in vitro. The methanol of K. senegalensis which exhibited varied from (81%) mortality with in 72h, at concentration 500 ppm; this was compared with Artemether which gave 85% inhibition at the same time. In conclusion: These studies conducted for K. senegalensis (bark) was proved to have potent anti-malarial activities against Plasmodium falciparum in vitro
URI: http://khartoumspace.uofk.edu/123456789/24261


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