University of Khartoum

Multinodular Thyroid Goiter And Risk Of Malignancy

Multinodular Thyroid Goiter And Risk Of Malignancy

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Title: Multinodular Thyroid Goiter And Risk Of Malignancy
Author: Rajab, Al-zahrani; Mohammed, MD, Al-Garni; Jabir, Alharbi; Tarek, Al-Shiakh; Adwan, Alsehli; Yousri, Hussein; Saleh, Al-Ghamdi; Mohammed, Satti; Saad, Alzahrani; Magdi, Salih
Abstract: Objective: to determine the incidence of occult malignancy in patients who had multinodular goiter and benign fine needle aspiration cytology (FNAC). Conventional medical sources recommend the use of fine needle aspiration cytology FNAC. For single thyroid nodules and the dominant nodule in multi nodular goiter (MNG). The essential role of fine needle aspiration cytology is to distinguish between benign and malignant nodules. Subjects and design: retrospective charts review at one tertiary care institute from January 2009 until January2014. Methods& Results: All patients who had multinodular goiter and benign FNAC for the suspicious nodule were reviewed after total thyroidectomy. 163 patients had multinodular goiter all of them underwent total thyroidectomy from January 2009 until January 2014. 28 patients had FNAC of papillary thyroid carcinoma and 8 had follicular lesion were excluded from the study. The remaining 135 patients had multinodular goiter and benign FNACs. Of those patients 37 (5 male and 32 females) about 27% had papillary thyroid carcinoma on permanent histopathology ranging between 0.2 to 2.5 cm one of them had follicular Variant of papillary carcinoma. Conclusion: Close monitoring of conservatively treated multinodular goiters is advised and the risk of malignancy in multinodular goiters with benign looking FNAC should not to be underestimated.
URI: http://khartoumspace.uofk.edu/123456789/25384


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