University of Khartoum

Accuracy of oral exfoliative cytology in Sudanese patients undergoing oral biopsy

Accuracy of oral exfoliative cytology in Sudanese patients undergoing oral biopsy

Show simple item record

dc.contributor.author Edris, Ali Mahmoud M.
dc.contributor.author Ahmed, Hussain Gadelkarim
dc.contributor.author Mohammed, Elneel Ahmed
dc.date 2016
dc.date.accessioned 2017-08-27T14:53:17Z
dc.date.available 2017-08-27T14:53:17Z
dc.date.submitted 2010
dc.identifier.uri http://khartoumspace.uofk.edu/123456789/25525
dc.description.abstract Introduction: Early detection of a premalignant or malignant oral lesions promises to improve the survival and the morbidity of patients suffering from these conditions. Oral exfoliative cytology (OEC) is a non-invasive method that is well accepted by the patient, and is therefore, suitable for screening at-risk population for early diagnosis of oral cancer. Objective: The purpose of this study is to investigate the value of OEC in the detection of oral premalignant and malignant lesions. Material and methods: In this hospital-based case-control study, cytological scrapes from buccal mucosa were obtained from 100 individuals, of whom 50 were patients with oral lesions ascertained as “cases” and 50 were clinically healthy volunteers ascertained as “controls”. All patients with oral lesions were also subjected to oral biopsy and histological examination. Results: Out of 50 cases studied, histopathology showed the presence of: Oral squamous cell carcinoma OSCC (n = 28), leukoplakia (n = 8), dysplasia (n = 3), and benign normal lesions (n = 11). In cytology, a specificity of 100%, sensitivity of 93% and accuracy of 92% were obtained for OSCC. Leukoplakia gave a specificity of 100%, a sensitivity of 87.5%, and an accuracy of 95%. Conclusion: Despite the small number of cases in this study, OEC is a useful method for detecting oral premalignant and malignant lesions. OEC can detect a number of pathological conditions that require management. en_US
dc.publisher uofk en_US
dc.subject oral lesions; exfoliative cytology; diagnosis en_US
dc.title Accuracy of oral exfoliative cytology in Sudanese patients undergoing oral biopsy en_US
dc.type Publication en_US
dc.Faculty Dentistry en_US

Files in this item

Files Size Format View

This item appears in the following Collection(s)

Show simple item record

Share

Search DSpace


Browse

My Account