University of Khartoum

Value of centrifugated liquid-based cytology by Papanicolaou and May-Grünwald in oral epithelial cells

Value of centrifugated liquid-based cytology by Papanicolaou and May-Grünwald in oral epithelial cells

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dc.contributor.author Ahmed, Hussain Gadelkarim
dc.contributor.author Idris, Ali Mahmmoud
dc.contributor.author Mohmed, Eneel Ahmed
dc.contributor.author Hussein, Mohammed Omer M.
dc.date 2017
dc.date.accessioned 2017-08-27T15:23:34Z
dc.date.available 2017-08-27T15:23:34Z
dc.date.submitted 2009
dc.identifier.uri http://khartoumspace.uofk.edu/123456789/25532
dc.description.abstract For many years, liquid-based cytology (LBC) has been developed for cervical cancer screening and not oral cancer, as it requires automated devices. The aim of this study was to compare the utility of centrifugated CLBC preparation with that of direct preparation in oral lesions, by Papanicolaou (Pap) and May Grünwald-Giemsa's (MGG) methods. A total of 100 consecutive cases of oral lesions were investigated. We compared the results obtained by the CLBC performed by cytocentrifugation with those obtained by direct smear applying Pap and MGG methods. The comparison between CLBC and direct smears was based on the thickening or adequacy of the smear, distribution of cells and staining quality. All smears in LBC and direct preparation were found adequate. For thickness of the smear, 40% and 42% were excellent, 33% and 30% were good, and 27% and 28% were acceptable by LBC and direct preparation, respectively. For the distribution of cells and scantiness of background elements, 92 (92%) smears of the LBC have revealed clear, well distributed smears, compared to 70 (70%) of those in direct preparation. For the staining quality with the Pap method, 39% and 69% were excellent staining quality, 25% and 20% were good, and 36% and 11% were acceptable for CLBC and direct preparation, respectively. In MGG method, 9% and 22% were excellent staining quality, 23% and 36% were good and 68% and 43% were acceptable for CLBC and direct preparation respectively. LBC performed by cytocentrifugation is inexpensive, and inadequate smears and background staining. en_US
dc.publisher uofk en_US
dc.title Value of centrifugated liquid-based cytology by Papanicolaou and May-Grünwald in oral epithelial cells en_US
dc.type Publication en_US
dc.Faculty Medical Laboratory Sciences en_US

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