Title:
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Brain Tuberculoma, an Unusual Cause of Stroke in a Child with Trisomy 21: A Case Report |
Author:
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Kheir, Abdelmoneim E M.; Ibrahim, Salah A.; Hamed, Ahlam A.; Yousif, Badreldin M.; Hamid, Farouk A.
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Abstract:
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Background: Tuberculosis remains a public health problem in developing countries and is associated with lethal
central nervous system complications. Intracranial tuberculomas occur in 13% of children with neurotuberculosis.
Patients with trisomy 21 have an increased risk for stroke, which usually stems from cardiovascular defects.
Case presentation: We report a case of a 12-year-old Sudanese boy with trisomy 21 who was presented to our
hospital with focal convulsions and right-sided weakness. The results of neuroimaging and histopathological
examinations were consistent with cerebral tuberculoma. The patient had a good initial response to antituberculosis
drugs and steroids. To the best of our knowledge, this is the first case report of multiple brain tuberculomas described
in a child with trisomy 21.
Conclusions: Patients with trisomy 21 have an increased risk for stroke. Our patient had an exceptional case of stroke
caused by tuberculoma. The present case emphasizes the need to consider tuberculomas in the differential diagnosis
of children with neurological symptoms living in areas of high tuberculosis incidence. |
URI:
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http://khartoumspace.uofk.edu/123456789/26011
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