University of Khartoum

Effect of Cigarette Smoking on some Liver Functions Test

Effect of Cigarette Smoking on some Liver Functions Test

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Title: Effect of Cigarette Smoking on some Liver Functions Test
Author: Ahmed, Walaa Adil; Fadlelmula, Tarig Mohamed; Mohammed, Liza Hamdi
Abstract: Background: Cigarette smoking is one of the 10 greatest contributors to global death and disease. Cigarette contains harmful chemicals such as carcinogenic, cytotoxic and free radicals, which are affect many organs. Our study aimed to assess the effects of dose response of tobacco exposure on liver function among male population in Khartoum-Sudan. Methodology: It is case control study which include hundred Sudanese participant smoker male, aged between (25 60 years), the participant divided into two groups, (50 smoker) and (50 non smoker) as control. The smoker group were further divided into moderate (0.5 1 pack/day) and heavy smoker (>1 pack/day) according to WHO classification. Blood sample was drawn for assessment of some liver function test, Aspartase amino transferase (AST), Alanine amino transferase (ALT), Alkaline phosphatase (ALP), serum total bilirubin and serum albumin. Results: The results showed that there was statistically significant in AST, ALT, ALP, serum total bilirubin and serum albumin, (pvalue 0.00,0.00,0.00,0.00 and0.00) respectively, when compared to control group. Conclusion: Cigarette smoking affects liver function regardless of number of Cigarette smoked per day and duration of smoking.
URI: http://khartoumspace.uofk.edu/123456789/26038


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