University of Khartoum

The Effect of Thyroid Function on Blood Coagulation among Patient with Thyroid Disorders in Elnehoud Teaching Hospital

The Effect of Thyroid Function on Blood Coagulation among Patient with Thyroid Disorders in Elnehoud Teaching Hospital

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Title: The Effect of Thyroid Function on Blood Coagulation among Patient with Thyroid Disorders in Elnehoud Teaching Hospital
Author: Abdalrahim, Arafa Habiballa Ibrahim
Abstract: Background: Thyroid diseases is the most common disorders special in kordofan highly incidence in women and has been diagnostic by lab findingpredominantly hypo and euothyroid than hyperthyroidism Objective: The aim of the study was to find out the association of serum thyroid hormons(T3/T4/TSH) and blood coagulation parameters (PT, INR, aPTT and platelets count) Materials &Methods: Case control study was done in elnehoud teaching hospital -Sudan from October 2014 to march 2015 in 174 patient ,101 pt diagnosed as case and other 73 as control , their age varied from 14to60 years old Serum thyroid hormones are measured by enzyme linked immune-sorbent assay(ELISA), prothrombin INR activated partial thromboplastin is measured by coagulometer. Platelets were counted by sysmex analyzer Result There is significantpositive correlation in prothrombin time in patients with hypothyroidism compared to control group with p-value (0.004) there is no significant relation in INR in patient with hypothyroidism compared to control group with p-value (0.646)) there is no significant relation in activation partial thromboplastin time inpatient with hypothyroidism compared to control group with p-value(0.697) there is significant negative correlation in platelets count in patient with hypothyroidism compared to control group with p-value(0.027) There is no significant correlation between prothrombin in patients with euothyroid compared to control group with p–value (0.178)there is no significant correlation between INR in patients with euothyroidsm compared to control group with p-value(0.646) there is no significant correlation in aPTT in patients with euothyrodism compared to control group with p-value(0.132) There is significant negative correlation in platelets count in patients with euothyroism compared tocontrol group with p-value(0.027).
URI: http://khartoumspace.uofk.edu/123456789/26129


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