University of Khartoum

Dental Caries and it’s Association with the Level of Salivary Calcium and Serum Alkaline Phosphatase among Patients with Type 2 Diabetes Mellitus

Dental Caries and it’s Association with the Level of Salivary Calcium and Serum Alkaline Phosphatase among Patients with Type 2 Diabetes Mellitus

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Title: Dental Caries and it’s Association with the Level of Salivary Calcium and Serum Alkaline Phosphatase among Patients with Type 2 Diabetes Mellitus
Author: Mohammed, Manhal Siragaldeen Abass
Abstract: Objective: The aim of this study was to focus on dental caries distribution and analyze it’s relationship with serum Alkaline Phosphatase and salivary Calcium, in diabetic patients. Methodology: A total of 146, (73 diabetic & 73 non diabetic ) age matched from( 30 to 70 years) individuals participated in this study, Decayed ,Missed, Filled teeth (DMFT) index was used for scoring dental caries, both groups were categorized according to the caries activity DMFT>10 categorized as high caries “caries active, and DMFT≤ 10 categorized as low caries, saliva & blood samples were collected Salivary calcium and Serum Alkaline phosphatase (ALP) were analyzed. All parameters were subjected to statistical analysis using (SPSS) version 20. Results: The mean of DMFT was significantly higher in diabetic than non diabetic. No statistical difference was found in ALP activity between diabetic and non diabetic patients, also no statistical difference was found in diabetic patients between high caries and low caries groups. Non diabetic patients showed significantly higher ALPV activity in high caries group when compared to low caries group. No statistical difference was found in salivary calcium concentrations between diabetic and non diabetic either high or low caries, Duration of diabetes and levels of fasting blood glucose didn’t show any significance with dental caries in diabetic patients Conclusion: Dental caries was significantly higher among diabetic patients but salivary calcium & serum ALP have no association with dental caries in diabetic patients. Serum ALP was significantly elevated in high caries non diabetic individuals
URI: http://khartoumspace.uofk.edu/123456789/27117


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