University of Khartoum

Pan African Plasmodium vivax and ovale Network: Refocusing on the parasites’ transmission, detection and elimination in Africa

Pan African Plasmodium vivax and ovale Network: Refocusing on the parasites’ transmission, detection and elimination in Africa

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Title: Pan African Plasmodium vivax and ovale Network: Refocusing on the parasites’ transmission, detection and elimination in Africa
Author: Quaye, Isaac; Moffatt, Stanley; Aleksenko, Larysa; Oevray, Claude; Yewhalaw, Delenasaw; Bruna, Djeunang; Torgby, Ruth-Ayanful; Abdel Hamid, Muzamil Mahdi; Nancy Duah; Giacomo Paganotti; Ben Gyan; Linda Amoah; Solomon Worku; Tjantilili Mosweunyane; Assefa Ashenafi Bahiti; Daniel Haiyambo; Harriet Akello Pasquale; Mimie Bitsie; Isidore Troare; Amidou Diarra; Eric Njunju1, Mamodou Cisse; Issiaka Soulama; Ragnessi Justin Savadogo; Saadou Issifou; Amadou Niangaly; Luis Bonavente; Beatrice Greco
Abstract: Background: In recent times, several countries in sub-Saharan Africa have reported cases of Plasmodium vivax (Pv) with a considerable number being Duffy negative. The burden of Pv and Plasmodium ovale (Po) which have hypnozoite forms appear to be more than acknowledged, playing roles in migrant and autochthonous infections. New approaches are required to attain elimination and eradication targets. Method: Pan African Vivax and Ovale Network (PAVON) is a new consortium of scientists working in Africa on Pv and Po in partnership with Merck Global Health Institute, Geneva, Switzerland, aiming to facilitate focus on Pv and Po by African NMCPs. Details of the modus operandi of the group is outlined. We have assessed reported survey detections of Pv and Po in the literature visa-vis migrant/travel infections worldwide from African countries. Results Many countries outside Africa, have reports of African migrant/travel infections of either Pv or Po or both. There is no congruence between country survey reports and migrant/travel infections. Some countries on course for elimination, have seen changes partly attributed to Pv and Po infections. These new observations query strategies that target only Plasmodium Falciparum (Pf) species, and why there is no congruence between country survey reports and migrant infections. Conclusion The burden of Pv and Po in Africa appears more than presently acknowledged. PAVON consortium aims to forge collaborations with NMCPs in Africa to increase focus on Pv and Po, facilitate training in standardized procedures for detection, and improve integrated management with active and reactive case detection.
URI: http://khartoumspace.uofk.edu/123456789/27937


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