University of Khartoum

Immunogenetic Control of Antibody Responsiveness in a Malaria Endemic Area

Immunogenetic Control of Antibody Responsiveness in a Malaria Endemic Area

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Title: Immunogenetic Control of Antibody Responsiveness in a Malaria Endemic Area
Author: ابوشامه, هند
Abstract: This study builds upon the established genetic control of antimalarial immune responses and prior association studies by using a family-based ap- proach, transmission disequilibrium testing, to identify immune response genes that influence antibody responses to Plasmodium falciparum infection in an endemic Tanza- nian population. Candidate polymorphisms are within the interleukin-1 (IL-1) gene cluster, the IL-10 promoter, Major histocompatibility complex class II and III, the 5q31-q33 region, and the T-Cell Receptor beta variable
Description: Immunogenetic Control of Antibody Responsiveness in a Malaria Endemic Area
URI: http://hdl.handle.net/123456789/6150
Date: 2008


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