University of Khartoum

THE ROLE OF MITOCHONDRIAL GENOME AND GLUTATHIONE S TRANSFERASES IN BREAST CANCER IN SUDAN

THE ROLE OF MITOCHONDRIAL GENOME AND GLUTATHIONE S TRANSFERASES IN BREAST CANCER IN SUDAN

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Title: THE ROLE OF MITOCHONDRIAL GENOME AND GLUTATHIONE S TRANSFERASES IN BREAST CANCER IN SUDAN
Author: Abdulrahman, Mai; Eltayeb, Muntaser
Abstract: Breast cancer is the most common type of cancer among women and the third leading cause of death after malaria and viral infections in Sudan. Mitochondria perform various functions which implicate them as contributors to human pathology including cancer. Growing molecular evidence suggests that cancer cells exhibit increased intrinsic Reactive oxygen species (ROS) stress, increased metabolic activity and mitochondrial malfunctions, which might initiate tumoregenesis and turn on the vicious circle of oncogenesis.
URI: http://hdl.handle.net/123456789/6331
Date: 2010-10


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