University of Khartoum

Prevalence of Specific Mutant Genes (D76N, C18R and R197H) In Sudanese Diabetics Type II Patients

Prevalence of Specific Mutant Genes (D76N, C18R and R197H) In Sudanese Diabetics Type II Patients

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Title: Prevalence of Specific Mutant Genes (D76N, C18R and R197H) In Sudanese Diabetics Type II Patients
Author: Ahmed, Nahla; Awad, Eltahir
Abstract: Diabetes mellitus (DM) is a group of metabolic disorders characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. Type 2 diabetes mellitus is a costly disease that affects over 100 million people worldwide and is a major cause of morbidity and mortality. The transcription factor, insulin promoter factor-1 (IPF-1) plays a central role in the development of the pancreas and the regulation of insulin gene expression in the β cells.
URI: http://hdl.handle.net/123456789/6381
Date: 2009


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