University of Khartoum

Effect of Clinical and Subclinical Hypothyroidism on some lipid values among Sudanese females

Effect of Clinical and Subclinical Hypothyroidism on some lipid values among Sudanese females

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Title: Effect of Clinical and Subclinical Hypothyroidism on some lipid values among Sudanese females
Author: Osman, Niamat
Abstract: This study composed of two parts, the first one a survey and the other one is experiment to estimate some lipids values among hypothyroidism and sub clinical hypothyroid females compared to euothyroid group. A survey was carried out for records of thyroid function test from the Radio Immuno Assay (RIA) laboratories in Sudan Atomic Energy Commission (SAEC). This was during the period from 1994-1996; the purpose was to explore the ratio of males to females, mean of their ages and the prevalence of hypothyroid function among them. About (4268) subjects visited the lab for thyroid function test (TFT), (3730) of them were found to be females while males were only about (538). Mean of their ages ranging between 30-50 years. For the experiment part, one hundred and twenty females were selected to participate in this study, were divided into three equal groups as hypothyroidism, sub clinical hypothyroidism cases and a third group of euothyroid individuals was used as control. The levels of some serum lipids were measured (cholesterol, TG, LDL and HDL).The effect of thyroid hypo function on lipid was as follows: 1/ the hypothyroidism group showed highly significant levels of serum cholesterol, LDL –cholesterol and TG. 2/ Serum cholesterol and LDL –cholesterol levels in group with sub clinical hypothyroidism slightly elevated, in comparison with euothyroid group that represented normal values of these fractions. In the present work a clear effect of the thyroid hormones levels was observed. The serum lipids values were influenced this was showed (p<0.0) as significant increase of the total cholesterol and LDLcholesterol values in hypothyroid females.
Description: 86 Pages
URI: http://khartoumspace.uofk.edu/handle/123456789/8591
Date: 2015-04-08


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