University of Khartoum

Changes in Blood Coagulation in HIV/AIDS patients in Sudan

Changes in Blood Coagulation in HIV/AIDS patients in Sudan

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Title: Changes in Blood Coagulation in HIV/AIDS patients in Sudan
Author: Ahmed, Mohammed
Abstract: This is a prospective Laboratory study conducted at both Omdurman Teaching Hospital and Khartoum Teaching Hospital, from the first of February till mid April 2006. The aim of the study was to assess changes in blood coagulation and basic haematological parameters in HIV/AIDS patients in SUDAN. Fourty patients were included in this study, 22 males& 18 females, their ages ranged between 18-65 years. Basic haematological parameters namely HB, WBC, platelet counts were done. Also porthrombin time , activated partial thromboplastin time, antiphospholipid antibodies and CD4 counts, were carried out. Anemia was found is 57.5% of patients, but the type of anemia were not determined. There was leucopenia in (45%) patients. Thrombocytopenia was detected in 20%of patients. In haemostatic profile, no changes were detected regarding prothrombin time or activated partial thromboplastin time. IgM antiphospholipid antibodies were found in 22.5% of patients, and VIII IgG antiphospholipid in 75%of patients. These antibodies were not associated with any clinical manifestations. CD4 count was done in 35& low in 34 patients(85%) (less than200/ul) while normal in 1 patient (2, 5%). The knowledge of these hematological abnormalities in HIV/AIDS patients allows more rational care of these patients.
Description: 112 Pages
URI: http://khartoumspace.uofk.edu/handle/123456789/8612
Date: 2015-04-08


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