University of Khartoum

Histological pattern of oesophageal tumours in Sudanese patients

Histological pattern of oesophageal tumours in Sudanese patients

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Title: Histological pattern of oesophageal tumours in Sudanese patients
Author: Mohamed, Maha
Abstract: Oesophageal tumours are either benign or malignant. Benign tumours are mostly mesenchymal in origin. With rare exceptions, malignant oesophageal tumours arise from the epithelial layer. This is a retrospective study conducted in Sudanese patients at Ibn Sina hospital and NHL. The aim of the study is to determine histopathological pattern, age and sex distribution of oesophageal tumours. The study comprised 102 patients of which 44 were males and 58 were females with a male to female ratio of 1:1.3. The age of all patients ranged between 29 – 90 with a mean of 65 years. In this study no benign tumour was identified and all the cases were malignant tumours the histology of which was SCC and adenocarcinoma. The SCC being predominant comprising 89.1 %, with a male to female ratio of 1:1.6. There is striking male predominance in adenocarcinoma (10:1) By revising the slides: 85 were SCC (83 %) , 4 basoloid squamous cell carcinoma (4%), 2 spindle cell carcinoma (2 %), 9 adenocarcinoma (9%), 1 case papillary carcinoma (1 % ) , one case signet ring cell carcinoma and 1 anaplastic carcinoma (1%). Invasive SCC represented the majority of cases (88%) while only 12% were intraepithelial. In conclusion benign tumours and other tumours like carcinoid, lymphomas etc are rare. SCC is the most common oesophageal cancer in Sudanese patients as it is the case worldwide. Intraepithelial neoplasia is under diagnosed and this raises the importance of screening programs.
URI: http://khartoumspace.uofk.edu/handle/123456789/8711
Date: 2015-04-09


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