University of Khartoum

THE EFFECT OF ALOE VERA ETHANOLIC EXTRACT ON BLOOD GLUCOSE LEVEL, , ON WISTER ALBINO RATS

THE EFFECT OF ALOE VERA ETHANOLIC EXTRACT ON BLOOD GLUCOSE LEVEL, , ON WISTER ALBINO RATS

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Title: THE EFFECT OF ALOE VERA ETHANOLIC EXTRACT ON BLOOD GLUCOSE LEVEL, , ON WISTER ALBINO RATS
Author: Khedir, Maha
Abstract: The hypoglycemic effect of ethanolic extract of Aloe verawas studied on hyperglycemic and normal Wister albino rats. The oral administration of 10 mg/kg B.wt of glibenclamide, (hypoglycemic drug), and two different concentrations 100, 500 mg/kg.B.wt Aloe veraextract to glucose loadedrats (2 mg/kg of 50% glucose solution) showed a lowering effect on blood glucose level compared to the control group. It was significant (P< 0.01) at a dose of 500 mg/kgB.wt 2 hours after treatment. Similar doses of Aloe veraextract orally administrated to normal rats for six days, has no significant lowering effect in plasma glucose level of animals. However, there were a significant reduction in body weight of rats received the Aloe verabut there were no significant effect on the relative livers weights. Histologically the liver were normal but there were increased on globet cell in the intestine.
URI: http://khartoumspace.uofk.edu/handle/123456789/8786
Date: 2015-04-09


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