University of Khartoum

Collaborative Translational Research and Control of Meningitis in Sudan

Collaborative Translational Research and Control of Meningitis in Sudan

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Title: Collaborative Translational Research and Control of Meningitis in Sudan
Author: Salih, Mustafa Abdalla M.
Abstract: Sudan lies within the meningitis belt and meningococcal disease has been one of its major problems throughout the twentieth century. Over 12,000 and 55,000 cases were recorded in the years 1935 and 1950 respectively; and during the period 1968-1980, over forty thousands (40,513) were inflicted with the disease of whom 1,220 have died. A collaborative translational research between the University of Khartoum and Uppsala University in Sweden managed to document the epidemiology, clinical features and complications of childhood acute bacterial meningitis (ABM) in Sudan during both an inter-epidemic (endemic) period (1985-1986), and the 1988 serogroup A epidemic; and to examine the phenotypic and genetic similarities and differences of Neisseria meningitidis strains isolated in Sudan and Sweden. A novel enzyme immunoassay test (Pharmacia Meningitis EIA-Test) was evaluated as a potential rapid diagnostic method for the detection of Haemophilus influenzae (HI) type b, Neisseria meningitidis (MC) and Streptococcus pneumoniae (PNC).
URI: http://khartoumspace.uofk.edu/handle/123456789/9954
Date: 2015-02


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