Major Genetic Variants of Glucose 6 Phosphate Dehydrogenase among Selected Sudanese Ethnic Groups
Major Genetic Variants of Glucose 6 Phosphate Dehydrogenase among Selected Sudanese Ethnic Groups
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Date
2010-01
Authors
abdalmuti, Abdalla
El-Tayeb, Muntaser
Journal Title
Journal ISSN
Volume Title
Publisher
uofk
Abstract
Background: The glucose 6 phosphate dehydrogenase (G6PD) gene is X chromosome
linked, and the deficiency in this enzyme is the most common known enzymopathy in
humans, and is usually, occurs due to single nucleotide substitution which varies from
population to other, these mutations accounts for more than 400 variants worldwide, but
usually few of them are common in certain populations. Here in Sudan and according to
the data from the surrounding area four variants (B, A, A- and Mediterranean) are
suspected to be more common, which were the ones included in this study.
Description
Keywords
Variant,Chromosome,Diseases