Effects of Fattening on some Biochemical Parameters in Sheep Infected With Morel’s Disease

Abstract

This study was conducted in the department of Biochemistry Faculty of Veterinary Medicine University of Khartoum. The aim of the study is to investigate the effects of fattening, on Sheep infected with Morel’s disease. The work targetd changes in parameters of lipids and protein metabolism that influenced by infection. Ten Hammary sheep of (8-10) month age, were selected for this study. They were divided into two groups, one group was subjected to fattening program and the other one fed roughages for maintenance. Then both groups were infected with Saph aureus sub sp anaerobeus, the causative agent of Morel’s disease. Blood samples collected twice before infection and after the ripening of the abscesses and also adipose tissue biopsy was taken once from around the ripen abscess. The study showed clear effects of acute infection on most of the parameters measured and fattening significantly influenced these effects. Blood lipids values were significantly affected: 1. Total lipids, total cholesterol and free fatt acids levels, were greatly decreased after infection and the difference was significant (P<0.05) in the fattened group. 2. Triacylglycerols levels, in contrast to other lipids, increased significantly (P<0.05) in both groups after infection. 3. Phospholipids were the only lipid parameter that remained constant in both groups after infection, it was not affected by fattening or infection. v Blood proteins values were also significantly affected: 1. Total proteins level decreased significantly (P<0.05)in both groups after infection. 2. Albumin values were found to be very low after infection, this effect was significant (P<0.05) in the fattened group. 3. In contrast to albumin, total globulins values were increased after infection and the difference was significant (P<0.05) in the fattened group. The PH, of the extract of the adipose tissue biopsy, in both groups, was acidic as 5.96 and 6.29 in the fattened and unfattened groups respectively, but the difference was not significant. The abscesses size increased following the grade of the body weight in both groups but the largest ones were found in the fattened group. The body temperature followed the same manner during abscess formation in both groups.