Clinical Pattern, Aetiology And Short Term Outcome Of Neonatal Seizures In Khartoum State
Clinical Pattern, Aetiology And Short Term Outcome Of Neonatal Seizures In Khartoum State
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Date
2015-04-07
Authors
Eisa, Ishag
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Abstract
This is a descriptive, cross sectional, hospital based study
conducted between August 2004 -February 2005.
Five hospitals representing Khartoum State were selected,
including Omdurman Maternity Hospital (OMH), Soba University
Hospital (SUH), Khartoum Children Emergency Hospital (KCEH),
Omdurman Children Emergency Hospital (OCEH) and Ahmed Gasim
Hospital (AGH).
The purpose was to study the clinical Pattern of neonatal
seizures, possible underlying causes and to determine short term
outcome in the acute illness and neonatal period.
Seventy five newborns with neonatal seizures from the first
attack and throughout the neonatal period were studied. The
admissions represented 2.3%, 1.5% of INCUs admissions in OMH
and SUH respectively and 0.21%, 0.23% and 0.07% of general
pediatric case admissions in KCEH, AGH and OCEH respectively. Of
the seventy five newborns, 61.33% developed seizures within the first
48 hours of age.
III
The study found that the neonatal sepsis and birth asphyxia
were the principal etiological factors in 53%, 25% of cases,
respectively.
The findings of the clinical pattern of the seizures were 55
(73.33%) multifocal, 10 (13.33%) focal, seven (9.33%) tonic, two
(2.7%) subtle and one (1.3%) myoclonic seizures.
Poor prognosis was associated with neonatal sepsis, birth
asphyxia, multifocal, focal seizures and development of seizure in the
first 48 hours of age. The mortality was 18 (24%) cases mainly during
the acute illness and only one during the neonatal period.
Detectable causes of neonatal seizures in our environment
appear to be potentially preventable by improved obstetric and
neonatal care. There is bad need also to provide modern facilities for
investigating newborn seizures in order to improve upon diagnostic
yield and better management.
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Keywords
Short Term Outcome Of Neonatal Seizures In Khartoum State