Input of Flow Cytometry in the Diagnosis of Primary Immune Deficiencies

Abstract

Over the past three decades, flow cytometry has emerged as an invaluable technology in clinical laboratories and has contributed significantly to investigate the immune system cell components. Its unparalleled ability to simultaneously identify characteristic physical cell properties, cell numbers, cell functions, and numerous cell gene products at rates of thousands of cells per second has resulted in the development of a large repertoire of diagnostic, prognostic, and monitoring assays