Intravenous Dexamethasone As Post Operative Antiemetic
Intravenous Dexamethasone As Post Operative Antiemetic
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Date
2015-04-14
Authors
Khidir, Rajabia
Journal Title
Journal ISSN
Volume Title
Publisher
UOFK
Abstract
The aim of this study is to evaluate the prophylactic anti-emetic effect of
intravenous dexamethasone in post operative nausea and vomiting.
The following were found to increase the incidence of PONV: Female
gender, history of PONV, history of motion sickness, post operative pain
and type of operation mainly laproscopic surgery.
One hundred fifty patients requiring general anesthesia for different
types of operations were enrolled in a randomized, double blind,
placebo-controlled study.
Fifty patients received dexamethasone 6mg intravenously group (A), 50
patients received dexamethasone 10mg i.v group (B) and 50 patients
taken as control group received normal saline 2ml i.v group (C) at the
induction of anesthesia.
We found that, the comparison between the three groups showed:
Group (A) 22% of patient had Nausea, 12% of patient had vomiting.
Group (B) 16% of patient had Nausea, 12% of patient had vomiting.
Group (C) 76% of patient had Nausea, 44% of patient had vomiting.
The study clearly showed that dexamethasone 10mg and 6mg
significantly decreased the incidence of postoperative vomiting, while
dexamethasone 10mg was more effective in reducing the incidence of
post operative nausea.
Description
73page
Keywords
Intravenous, Dexamethasone, Post, Operative ,Antiemetic