Prevalence of Specific Mutant Genes (D76N, C18R and R197H) In Sudanese Diabetics Type II Patients

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Date
2009
Authors
Ahmed, Nahla
Awad, Eltahir
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Publisher
uofk
Abstract
Diabetes mellitus (DM) is a group of metabolic disorders characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. Type 2 diabetes mellitus is a costly disease that affects over 100 million people worldwide and is a major cause of morbidity and mortality. The transcription factor, insulin promoter factor-1 (IPF-1) plays a central role in the development of the pancreas and the regulation of insulin gene expression in the β cells.
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Keywords
Patients,Specific Mutant Genes
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