Role of Goats in Transmission of Schistosoma mansoni Infection

dc.Degree M.Sc en_US
dc.Faculty Veterinary Science en_US
dc.co.Supervisor Elawad Mohamed Elhassan
dc.co.Supervisor Elsayed Elsiddig Elowni
dc.contributor.advisor Elgailani Ali Elamin en_US
dc.contributor.author Ali, Fatima Hassan Mohamed Ali
dc.date.accessioned 2015-06-22T12:52:01Z
dc.date.available 2015-06-22T12:52:01Z
dc.date.issued 2015-06-22
dc.date.submitted 1999
dc.description.abstract The present work was carried out to verify the role of goats in transmission of Schistosoma mansoni. Nine goats were used. A group of 6 goats was infected with S. mansoni cercariae and another group of 3 goats was kept as control. The animals were kept under observation for 9 months and parasitological examination was weekly carried out during this period. Five of the experimental animals did not pass eggs in the faeces and the one remaining passed eggs only on day 177 after infection. All animals showed mature worms on perfusion. Histopathological examination showed presence of inflammation around eggs in both liver and intestine as evident by cellular infiltration and granuloma formation. Humoral immunity in experimental animals was assessed using ELISA to detect IgG antibodies against whole worm homogenate antigen. Antibody titre, as measured by optical density, varied during different periods with the level being significantly elevated in the 8th month in the infected group compared with the control. Determination of the level of bilirubin in experimentally infected animals showed a rise throughout the experiment. This rise was most pronounced in the 32nd week. The level of albumin in contrast decreased reaching its lowest level in week 38. It is concluded that goats can be experimentally infected with S. mansoni and the worms establishing could reach egg producing stage. Such eggs may not be passed outside the host possibly because of an operative immune response. It is concluded that goats may have a minor role, if any, in the transmission of S. mansoni. en_US
dc.identifier.uri http://khartoumspace.uofk.edu/handle/123456789/14171
dc.language.iso en en_US
dc.publisher University of Khartoum en_US
dc.subject Role of Goats in Transmission of Schistosoma mansoni Infection en_US
dc.title Role of Goats in Transmission of Schistosoma mansoni Infection en_US
dc.type Thesis en_US
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