Haematological Manifestations Associated With Malignant Solid Neoplasms In Sudanese Patients

Abstract

This is a prospective descriptive study which was conducted in Khartoum teaching hospital and (The Radiation & isotopes centre - Khartoum), during the period between September 2004 – January 2005, to determine the prevalence of haematological changes in patients with solid malignant tumours, focusing more on anaemia. 103 of patients already diagnosed as having malignant solid neoplasms were reviewed for their haematological changes 75.7% of the patients had anaemia regardless of the stage of disease compared to 72% in study done in western countries (32). Other haematological changes observed were high E.S.R seen in 70 patients (68)% and high T.W.B.C. (41.7%) . 11 pts. (10.7%) proved to have hypercoagulable state, 2 patients (1.9%) had polycythaemia, 8 patients (7.8%) developed DVT and 1 patient (IVC) thrombosis shown by CT-scan. 19.2% of the patients presented with bleeding in a form of frank rectal or vaginal bleeding, epistaxis, haemoptysis, melaena or haematuria.