The Effect of Fruit Extract of Randia nilotica on Miracidia and Cercariae of Schistosoma mansoni and on Biomphalaria pfeifferi and Bulinus truncatus Snails

Abstract

The aqueous filtered and unfiltered extract of the fruits of the plant Randia nilotica (Locally name as Shagarat EL-Murfaein) were assessed as molluscicides against Biomphalaria pfeifferi and Bulinus truncatus as well as their effect on cercariae and miracidia of Schistosoma mansoni. The plant was tested on uninfected Biomphalaria pfeifferi and Bulinus truncatus, the results showed that unfiltered extracts were found relatively more potent than filtered one (i.e. 100 % was attained at 90 ppm and 80 ppm) respectively. While filtered extract tested on uninfected Biomphalaria pfeifferi and Bulinus truncatus (100 % was attained at 100 ppm and 90 ppm) respectively. The effect of unfiltered extract on infected Biomphalaria pfeifferi produced 100 % mortality in concentration of 70 ppm. The activity of the plant on cercariae and miracidia revealed that cercariae was more resistance than miracidia (i.e.50 ppm killed all cercariae within 3 hours while killed miracidia within 2 hours. IV The results were statistically analyzed and discussed and the findings were promising and could open new avenues for the practical use of the plant at the field.