Incidence of Epstein-Barr Virus in Pediatric Leukemia in the Sudan

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Date
2015
Authors
Gadelkarim, Hussain
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Journal ISSN
Volume Title
Publisher
University of Khartoum
Abstract
This study screened 80 pediatric patients with leukemia and 20 healthy controls, from Sudan, for the presence of Epstein-Barr virus. Latent membrane protein 1 (LMP1) gene transcripts were found in 29 (36.3%) of 80 patients but in none of the controls (P < .0001). The high incidence of LMP1 in these patients, strongly suggests the role of Epstein-Barr virus in the etiology of pediatric leukemia in the Sudan.
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Keywords
Epstein-Barr virus, Latent membrane protein 1, Lymphoid leukemic, Pediatric, Sudan
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