The Effect Of Fresh Crushed Garlic Bulbs (Allium Sativum)On Plasma Cholesterol And Triglycerides In Cholesterol Fed Rats
The Effect Of Fresh Crushed Garlic Bulbs (Allium Sativum)On Plasma Cholesterol And Triglycerides In Cholesterol Fed Rats
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Date
2015-04-09
Authors
Mohamed, Maha
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Publisher
UOFK
Abstract
The aim of this study was to investigate the effect of fresh crushed
garlic bulbs on plasma total cholesterol (TC), low density lipoprotein
(LDL), high density lipoprotein (HDL) and triglycerides (TG) levels in an
induced hypercholesterolemic Wistar albino rats.
Twenty male Wistar albino rats were used in this study. They were
allotted to four groups A, B, C and D. Group A ( control group) received
a basal diet, group B received a basaldiet with 2% cholesterol, group C
received a basal diet with 2% cholesterol and 4% garlic, group D received
a basal diet with 2% cholesterol and 8% garlic.
The results showed that, plasma TC, LDL-cholesterol and TG
levels were increased significantly (P< 0.05) in group B compared to the
control group, while HDL-cholesterol level was decreased significantly.
In group C, the plasma levels of TC and LDL-cholesterol were
decreased significantly (P< 0.05), however, HDL-cholesterol was
increased compared to group B, but no significant difference in the level
of TG was observed compared togroup B. However group C showed
significantly (P< 0.05) higher levels of TC and TG and non- significant
difference in LDL-cholesterol and HDL-cholesterol levels compared to
the control group.
The plasma levels of TC, LDL-cholesterol and TG in group D were
decreased significantly (P< 0.05) compared to group B, while HDLcholesterol was increased. The levels of TC, LDL-cholesterol, HDLcholesterol and TG in group D were nonsignificantly different compared
to the control group
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Keywords
Garlic Bulbs,Plasma Cholesterol,Fed Rats