Infectious Bursal Disease Vaccine in The Sudan.

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Date
2015-06-23
Authors
Mohamed Abdel Mageed Abdu Abbass, Abbass
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UOFK
Abstract
This study was carried out to control virulent infectious bursal disease (IBD) by massive vaccination. lBD vaccines were given to chicks at different ages so as to identify the best vaccination program whereby a good level of antibody response can be obtained and to investigate any suppression effect of IBD vaccines on the ND vaccination. Susceptible 14 days old chicks showed no response to D78 IBD vaccine two weeks after vaccination but there was a slight response (20%) in the second group (14 days old) two weeks after the first vaccination and a good response (80%) two weeks after the second vaccination. A complete response (100%) was found two weeks after the first vaccination in susceptible chicks of four weeks old birds which had D78 IBD vaccine either by the recommended dose or double dose, hence there was some benefits to repeat vaccination or give double dose of the vaccine. The optimum time of the second vaccination by D78 was two weeks after the first vaccination. Susceptible 14 days old chicks showed a slight response (13.5%) to 228E IBD vaccine two weeks after the first vaccination. The percentage of chicks vaccinated at 7, 14 and 21 days of age that showed immune response to lBD were 20, 40 and 85%, respectively (two weeks after first vaccination). A complete response was recorded two weeks after the second vaccination by 228E. IBD vaccine (228E) caused slight suppression of the immune response to ND vaccination; it was more effective when used at early ages. Booster dose with 228E gave a good response in chick's primary vaccinated with the intermediate vaccine. Maternal immunity interferes with early age vaccination, it waned completely in the 4th week of age hence the best time for vaccination of maternally immune chicks was 21 days old. Yolk and serum gave comparable results with slight differences for detecting antibodies to IBD so yolk can be used instead of serum for seromonitoring.
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Infectious Bursal Disease Vaccine in The Sudan
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