Toxicity of Three Indigenous Plants to Sheep and Goats

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Nagi Ibrahim El Dirdiri, El Dirdiri
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The sequential development of clinical signs and lesions in the organs of Nubian goats and Desert sheep fed on Datura stramonium (Sakaran), Cadaba rotundifolia (Kurmut), Aristolochia bracteata (Um Galagel) and mixtures of the latter plants in certain proportions was studied. Kidney and liver functions were tested and the results were correlated with pathological and clinical changes. Disturbance in locomotion, hyperaesthesia, rapid respiration, reduced water intake and trembling were the main signs of D. stramonium poisoning in goats and sheep. There was an increase in aspartate amino-transferase activity and ammonia concentration and a decrease in the concentration of total protein and magnesium in the serum of D. stramonium poisoned animals. Clinical signs in goats and sheep fed on C. rotundifolia were pronounced depression, diarrhoea, frothing at the mouth, dyspnoea, ataxia, loss of condition and recumbency. The lesions consisted of diffuse haemorrhage in the abomasum, heart and lungs, catarrhal enteritis, erosions of the intestinal mucous membrane, degeneration and/or necrosis of the cells of the renal tubules and fatty changes and necrosis in the liver. These changes were correlated with those in serum constituents and blood cells. Diarrhoea, dyspnoea, tympany, arching of the back, loss of condition and of hair from the back were the prominent signs of A. bracteata poisoning in goats. The main pathological changes were haemorrhages in the lungs, heart and kidneys, fatty change and congestion of the liver, catarrhal abomasitis and enteritis and straw-coloured fluid in serous cavities. An increase in GOT activity, ammonia and urea concentrations and a decrease in concentrations of total protein and magnesium were detected in serum of A. bracteata poisoned goats. The effects of C. rotundifolia and A. bracteata were additive in goats.
Toxicity of Three Indigenous Plants to Sheep and Goats